The natural history of sporadic non-ampullary duodenal epithelial tumors: Can we wait and see?

Yoshiki Sakaguchi, Yosuke Tsuji, Tetsuo Ushiku, Dai Kubota, Junichi Sato, Miho Obata, Rina Cho, Sayaka Nagao, Nobuyuki Sakuma, Naoki Tamura, Yuko Miura, Kazushi Fukagawa, Daisuke Ohki, Hiroya Mizutani, Chihiro Takeuchi, Yu Takahashi, Chihiro Minatsuki, Keiko Niimi, Nobutake Yamamichi, Kazuhiko Koike

研究成果: ジャーナルへの寄稿記事査読

6 被引用数 (Scopus)

抄録

Objectives: The natural history of sporadic non-ampullary duodenal epithelial tumors (SNADETs) is poorly documented. The aim of this study was to evaluate the history of SNADETs in patients where immediate resection could not be performed. Methods: This is a single-center retrospective study of 86 consecutive cases of SNADETs who did not undergo immediate resection and were followed-up with upper gastrointestinal endoscopy for more than 6 months. Results: During a follow-up period of 36.8 (6.0–613.0) months, macroscopic progression was admitted in eight (9.3%). Of these, the final histology in four was adenocarcinoma, and three cases demonstrated submucosal invasion. Rates of macroscopic progression at 150 months after detection were 11.1%, 16.7%, and 30.0% for SNADETs <5 mm, <10 mm, and ≥10 mm, respectively. Conclusion: The overall risk of SNADETs progressing to invasive cancer is low. However, changes in macroscopic size or shape of SNADETs signify a high risk of progression to invasive cancer.

本文言語英語
論文番号e9
ジャーナルDEN Open
1
1
DOI
出版ステータス出版済み - 4月 2021
外部発表はい

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