The expression of sialyl Lewis X in canine and feline mammary gland tumors

Takayuki Nakagawa; Rina Uyama; Emi Ohashi; Tomoko Takahashi; Sung Hyeol Hong; Manabu Mochizuki; Satoru Matsunaga; Ryouhei Nishimura; Nobuo Sasaki

doi:10.1292/jvms.64.949

The expression of sialyl Lewis X in canine and feline mammary gland tumors

Takayuki Nakagawa, Rina Uyama, Emi Ohashi, Tomoko Takahashi, Sung Hyeol Hong, Manabu Mochizuki, Satoru Matsunaga, Ryouhei Nishimura, Nobuo Sasaki

The University of Tokyo

研究成果: ジャーナルへの寄稿 › 記事 › 査読

11 被引用数 (Scopus)

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The expression of sialyl Lewis X (sLe(x)) in 93 canine and 15 feline mammary gland tumors (MGT) obtained by surgical resection at Veterinary Medical Center, the University of Tokyo was examined by immunohistochemistry. Their clinicopathological features and prognosis were also reviewed. Approximately 60% of MGT tissues showed sLe(x) positive expressions, while all normal mammary gland tissues were negative. However, its expression was not correlated with clinicopathological features and prognosis significantly. This study suggests that sLe(x) may be a tumor-associated antigen in canine and feline MGTs.

本文言語	英語
ページ（範囲）	949-952
ページ数	4
ジャーナル	Journal of Veterinary Medical Science
巻	64
号	10
DOI	https://doi.org/10.1292/jvms.64.949
出版ステータス	出版済み - 10月 2002
外部発表	はい

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abstract = "The expression of sialyl Lewis X (sLe(x)) in 93 canine and 15 feline mammary gland tumors (MGT) obtained by surgical resection at Veterinary Medical Center, the University of Tokyo was examined by immunohistochemistry. Their clinicopathological features and prognosis were also reviewed. Approximately 60% of MGT tissues showed sLe(x) positive expressions, while all normal mammary gland tissues were negative. However, its expression was not correlated with clinicopathological features and prognosis significantly. This study suggests that sLe(x) may be a tumor-associated antigen in canine and feline MGTs.",

keywords = "Canine, Feline, Mammary gland tumor",

author = "Takayuki Nakagawa and Rina Uyama and Emi Ohashi and Tomoko Takahashi and Hong, {Sung Hyeol} and Manabu Mochizuki and Satoru Matsunaga and Ryouhei Nishimura and Nobuo Sasaki",

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AU - Uyama, Rina

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AU - Takahashi, Tomoko

AU - Hong, Sung Hyeol

AU - Mochizuki, Manabu

AU - Matsunaga, Satoru

AU - Nishimura, Ryouhei

AU - Sasaki, Nobuo

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N2 - The expression of sialyl Lewis X (sLe(x)) in 93 canine and 15 feline mammary gland tumors (MGT) obtained by surgical resection at Veterinary Medical Center, the University of Tokyo was examined by immunohistochemistry. Their clinicopathological features and prognosis were also reviewed. Approximately 60% of MGT tissues showed sLe(x) positive expressions, while all normal mammary gland tissues were negative. However, its expression was not correlated with clinicopathological features and prognosis significantly. This study suggests that sLe(x) may be a tumor-associated antigen in canine and feline MGTs.

AB - The expression of sialyl Lewis X (sLe(x)) in 93 canine and 15 feline mammary gland tumors (MGT) obtained by surgical resection at Veterinary Medical Center, the University of Tokyo was examined by immunohistochemistry. Their clinicopathological features and prognosis were also reviewed. Approximately 60% of MGT tissues showed sLe(x) positive expressions, while all normal mammary gland tissues were negative. However, its expression was not correlated with clinicopathological features and prognosis significantly. This study suggests that sLe(x) may be a tumor-associated antigen in canine and feline MGTs.

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The expression of sialyl Lewis X in canine and feline mammary gland tumors

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