The diagnosis of exogenous lipoid pneumonia caused by the silent aspiration of vegetable oil using a lipidomic analysis

Tetsuo Shimizu, Yoshiko Nakagawa, Yuko Iida, Kentaro Hayashi, Yoshihiro Sato, Shuichiro Maruoka, Noriaki Takahashi, Yasuhiro Gon

研究成果: ジャーナルへの寄稿記事査読

9 被引用数 (Scopus)

抄録

We herein report a case of refractory exogenous lipoid pneumonia that was successfully attributed to vegetable oil through a lipidomic analysis of bronchoalveolar lavage fluid (BALF). As a 25-year-old woman diagnosed with lipoid pneumonia experienced repeated exacerbations and improvement, we performed a BALF lipidomic analysis. The major lipid components were oleic acid, linoleic acid, and α-linolenic acid, which are constituents of vegetable oil. She stopped consuming any vegetable oil and has since experienced no instances of lipoid pneumonia relapse. A lipidomic analysis appears to be useful for identifying causative lipids, since patients with lipoid pneumonia are sometimes unaware of aspiration episodes.

本文言語英語
ページ(範囲)409-414
ページ数6
ジャーナルInternal Medicine
59
3
DOI
出版ステータス出版済み - 1 2月 2020

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