Real-Time Tissue Elastography for the Diagnosis of Lymph Node Metastasis in Oral Squamous Cell Carcinoma

Naomi Ishibashi, Kenji Yamagata, Hiroyoshi Sasaki, Kahori Seto, Yoshiko Shinya, Hiroyuki Ito, Keiji Shinozuka, Toru Yanagawa, Kojiro Onizawa, Hiroki Bukawa

研究成果: ジャーナルへの寄稿記事査読

35 被引用数 (Scopus)

抄録

We compared conventional ultrasound (US) B-mode, color Doppler and elastographic assessment of lymph node (LN) stiffness against pathological findings from surgical samples, to determine the most useful factors for identifying LN metastases. Seventy-one LNs in 19 patients with oral squamous cell carcinoma (OSCC) were examined. Using our new system, elastography images were scored from 1-5. The score 1-4 were correlated with the blue area of each LN, which indicated increased stiffness: (1) none; (2) <50%; (3) 50%; or (4) >50%. A score 5 indicated central necrosis and did not correlate with the blue area. We found significant differences in minimal diameter, shape index, margin, internal structure, hilus presence or absence, elastography score and percentage of blue area between metastatic and nonmetastatic LNs. Stepwise regression analysis identified elastography score 3-5 as an independent significant LN metastatic factor, suggesting that our scoring system may be useful for accurately diagnosing metastatic LNs.

本文言語英語
ページ(範囲)389-395
ページ数7
ジャーナルUltrasound in Medicine and Biology
38
3
DOI
出版ステータス出版済み - 3月 2012
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