Mucosal vaccines for oral disease

Tomoko Kurita-Ochiai, Tomomi Hashizume-Takizawa, Ryoki Kobayashi, Masafumi Yamamoto

研究成果: 書籍の章/レポート/Proceedings査読

4 被引用数 (Scopus)

抄録

Recent research and epidemiological studies have revealed that oral infectious diseases such as caries and periodontal diseases can trigger various systemic diseases, including diabetes, arteriosclerosis, infective endocarditis, myocardial infarction, rheumatoid arthritis, preterm birth, low birth weight, and intraoral infections. In addition, clinical problems include aspiration pneumonia caused by intraoral bacteria, which can cause death, and oral diseases and dental care of cancer treatment patients. Thus it can be said that infectious diseases occurring within the oral cavity have a great influence on the whole body in various forms. Therefore, it is urgent to develop a preventive vaccine against pathogenic bacteria of dental caries and periodontal diseases. Mucosal immunity is the optimal method for preventing infection in the oral cavity because it is where mucosal and systemic immunity intersect. In this chapter, the latest technologies and strategies of immunotherapy and vaccine development for preventing the onset of dental caries and periodontal diseases are introduced.

本文言語英語
ホスト出版物のタイトルMucosal Vaccines
ホスト出版物のサブタイトルInnovation for Preventing Infectious Diseases
出版社Elsevier
ページ649-661
ページ数13
ISBN(電子版)9780128119242
ISBN(印刷版)9780128119259
DOI
出版ステータス出版済み - 1 1月 2019

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