Motion-frozen myocardial perfusion SPECT improves detection of coronary artery disease in obese patients

Yasuyuki Suzuki, Piotr J. Slomka, Arik Wolak, Muneo Ohba, Shoji Suzuki, De Yang Ling, Guido Germano, Daniel S. Berman

研究成果: ジャーナルへの寄稿記事査読

33 被引用数 (Scopus)

抄録

In this study, we compared the diagnostic performance of the standard SPECT with motion-frozen (MF) myocardial perfusion SPECT (MPS) in obese patients. Methods: A total of 90 consecutive obese patients (body mass index, 30.1-46.8, average, 34.3 6 3.6; age, 63 6 12 y; 30% women) underwent standard supine rest 201Tl/stress 99mTc dual-isotope gated MPS and cardiac catheterization within 3mo. MF images were obtained by nonlinear warping of cardiac phases to the end-diastolic position. Total perfusion deficit (TPD) was obtained for summed (S-TPD) and motion-frozen (MF-TPD) datasets with sex-specific standard and MF normal limits. Results: The area under the receiver-operating-characteristic (ROC) curve for detection of coronary artery disease (CAD) by MF-TPD was significantly larger than that for S-TPD (0.93 ± 0.25 vs. 0.88 ± 0.32, P < 0.05). MF-TPD had higher specificity (77% vs. 55%, P < 0.05) and accuracy (89% vs. 80%, P < 0.05) than did S-TPD. Conclusion: MF processing of MPS improves CAD detection in obese patients.

本文言語英語
ページ(範囲)1075-1079
ページ数5
ジャーナルJournal of nuclear medicine : official publication, Society of Nuclear Medicine
49
7
DOI
出版ステータス出版済み - 1 7月 2008
外部発表はい

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