Marked improvement of breathing status by surgical mandibular advancement in a patient with Treacher-Collins syndrome

Shouhei Ogisawa, Yuta Sawatani, Michiko Shimura, Akio Himejima, Morio Tonogi, Hitoshi Kawamata

研究成果: ジャーナルへの寄稿記事査読

1 被引用数 (Scopus)

抄録

Treacher-Collins syndrome (TCS) is an autosomal dominant disease. TCS newborns have high mortality due to upper airway obstruction. Here, we reported a successful surgical approach in an adult patient with TCS who showed severe sleep apnea. The patient was a 32-year-old female who was diagnosed with obstructive sleep apnea (apnea hypopnea index: 116.1 /hr, apnea index: 75.2 /hr, hypopnea index: 40.8 /hr). Cephalometric analysis showed poor mandibular development (SNA: 80°, SNB: 67°, ANB: 11°) and deformity of nostril. We conducted surgical mandibular advancement, functional genioplasty, and expansion of the piriform aperture. Cephalometric analysis after surgery found improved skeletal morphology (SNA: 80°, SNB: 73°, ANB: 7°). Comparison of three-dimensional imaging before and after surgery showed that the airway had expanded. Polysomnography after surgery showed improvement to normal values (apnea hypopnea index : 2.7 /hr, apnea index: 0.8 /hr, hypopnea index: 1.9 /hr). Surgical mandibular advancement and functional genioplasty expanded the airway, and shaving of the piriform aperture corrected nasal respiratory disorder. Then, these surgical procedures improved severe sleep apnea in this patient.

本文言語英語
ページ(範囲)484-487
ページ数4
ジャーナルJournal of Oral and Maxillofacial Surgery, Medicine, and Pathology
32
6
DOI
出版ステータス出版済み - 11月 2020

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