Inadequate sleep duration may attenuate the anti-inflammatory effects of fish consumption in a healthy Japanese population: A cross-sectional study

Shigemasa Tani, Kazuhiro Imatake, Yasuyuki Suzuki, Tsukasa Yagi, Atsuhiko Takahashi, Naoya Matsumoto, Yasuo Okumura

研究成果: ジャーナルへの寄稿記事査読

2 被引用数 (Scopus)

抄録

High fish consumption may be associated with lower inflammation, suppressing atherosclerotic CVD (ASCVD). Long sleep duration, as well as short sleep, may contribute to inflammation, thus facilitating ASCVD. This study investigated the overall association between fish consumption, sleep duration and leucocytes count. We conducted a cross-sectional study between April 2019 and March 2020 with a cohort of 8947 apparently healthy participants with no history of ASCVD (average age, 46·9 ± 12·3 years and 59 % males). The average frequency of fish consumption and sleep duration were 2·13 ± 1·26 d/week and 6·0 ± 0·97 h/d. Multivariate linear regression analysis revealed that increased fish consumption was an independent determinant of sleep duration (β = 0·084, P < 0·0001). Additionally, habitual aerobic exercise (β = 0·059, P < 0·0001) or cigarette smoking (β = -0·051, P < 0·0001) and homoeostasis model assessment-insulin resistance (HOMA-IR) (β = -0·039, P = 0·01) were independent determinants of sleep duration. Furthermore, multivariate linear regression analysis identified fish consumption as an independent determinant of leucocytes count (β = -0·091, P < 0·0001). However, a significant U-shaped curve was found between leucocytes count and sleep duration, with 6-7 h of sleep as the low value (P = 0·015). Higher fish consumption may be associated with a lower leucocytes count in the presence of adequate sleep duration and healthy lifestyle behaviors. However, long sleep duration was also related to increased inflammation, even in populations with high fish consumption. Further studies are needed to clarify the causality between these factors.

本文言語英語
ページ(範囲)2142-2152
ページ数11
ジャーナルBritish Journal of Nutrition
129
12
DOI
出版ステータス出版済み - 28 6月 2023

フィンガープリント

「Inadequate sleep duration may attenuate the anti-inflammatory effects of fish consumption in a healthy Japanese population: A cross-sectional study」の研究トピックを掘り下げます。これらがまとまってユニークなフィンガープリントを構成します。

引用スタイル