Usefulness of Local Therapy in Elderly Breast Cancer Patients with Distant Metastases

Kenichi Sakurai, Shigeru Fujisaki, Shuhei Suzuki, Keita Adachi, Yuki Masuo, Saki Nagashima, Yukiko Hara, Katsuhisa Enomoto, Ryouichi Tomita, Kenji Gonda, Tomohiro Hirano, Sadao Amano

Research output: Contribution to journalArticlepeer-review


We investigated the usefulness of local therapy in elderly breast cancer patients with distant metastases. Sixty-four elderly breast cancer patients were encountered during 10 years. Fifty-one patients had complications. The proportion of endocrine receptor-positive tumors was 95.2%. Patients who had metastases at the first visit represented 22.6% of the study group. Advanced-stage cancers were recognized in elderly patients than other patients. The mean observation time for all the patients was 7.4 years. The mortality from cancer was 6.5%, and the mortality from other diseases was 58.1%. We divided the patients into 2 groups, the non-metastases group (group A, n=48), and the metastases group (group B, n=14). There were no significant differences between groups A and B in the rates of endocrine receptor-positive tumors, surgery rate, and survival rate. These results suggest that endocrine therapy without surgery should be considered in elderly breast cancer patients with endocrine receptor-positive tumors.

Original languageEnglish
Pages (from-to)1503-1505
Number of pages3
JournalJapanese Journal of Cancer and Chemotherapy
Issue number12
Publication statusPublished - 1 Nov 2015


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