The expression of sialyl Lewis X in canine and feline mammary gland tumors

Takayuki Nakagawa, Rina Uyama, Emi Ohashi, Tomoko Takahashi, Sung Hyeol Hong, Manabu Mochizuki, Satoru Matsunaga, Ryouhei Nishimura, Nobuo Sasaki

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


The expression of sialyl Lewis X (sLe(x)) in 93 canine and 15 feline mammary gland tumors (MGT) obtained by surgical resection at Veterinary Medical Center, the University of Tokyo was examined by immunohistochemistry. Their clinicopathological features and prognosis were also reviewed. Approximately 60% of MGT tissues showed sLe(x) positive expressions, while all normal mammary gland tissues were negative. However, its expression was not correlated with clinicopathological features and prognosis significantly. This study suggests that sLe(x) may be a tumor-associated antigen in canine and feline MGTs.

Original languageEnglish
Pages (from-to)949-952
Number of pages4
JournalJournal of Veterinary Medical Science
Issue number10
Publication statusPublished - Oct 2002
Externally publishedYes


  • Canine
  • Feline
  • Mammary gland tumor


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