Successful Therapeutic Hypothermia in a Patient with Drug-Induced J Waves and Cardiac Arrest: A Case Report

Jun Sato; Tsukasa Yagi; Erika Shimada; Masashi Kobori; Kazuhiro Watanabe; Tsukasa Kuwana; Nobutaka Chiba; Takeshi Saito; Kosaku Kinoshita

doi:10.1089/ther.2023.0041

Successful Therapeutic Hypothermia in a Patient with Drug-Induced J Waves and Cardiac Arrest: A Case Report

Jun Sato
, Tsukasa Yagi
, Erika Shimada
, Masashi Kobori
, Kazuhiro Watanabe
, Tsukasa Kuwana
, Nobutaka Chiba
, Takeshi Saito
, Kosaku Kinoshita

School of Medicine

Nihon University

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

A 50-year-old man was admitted to our hospital with hypotension and bradycardia after receiving high doses of atenolol, amlodipine, and etizolam. He had a drug-induced J wave on electrocardiography and subsequently underwent cardiac arrest. The patient was successfully rescued by venoarterial extracorporeal membrane oxygenation (VA-ECMO) and a good neurological outcome was achieved with therapeutic hypothermia (TH). In patients with J waves, TH is thought to increase the J waves and cause fatal arrhythmias, but in this case, rapid cooling with VA-ECMO allowed the patient to successfully complete TH.

Original language	English
Pages (from-to)	230-233
Number of pages	4
Journal	Therapeutic Hypothermia and Temperature Management
Volume	13
Issue number	4
DOIs	https://doi.org/10.1089/ther.2023.0041
Publication status	Published - 1 Dec 2023

Keywords

J wave
beta-blocker
calcium channel blocker
extracorporeal cardiopulmonary resuscitation
therapeutic hypothermia

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10.1089/ther.2023.0041

Cite this

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title = "Successful Therapeutic Hypothermia in a Patient with Drug-Induced J Waves and Cardiac Arrest: A Case Report",

abstract = "A 50-year-old man was admitted to our hospital with hypotension and bradycardia after receiving high doses of atenolol, amlodipine, and etizolam. He had a drug-induced J wave on electrocardiography and subsequently underwent cardiac arrest. The patient was successfully rescued by venoarterial extracorporeal membrane oxygenation (VA-ECMO) and a good neurological outcome was achieved with therapeutic hypothermia (TH). In patients with J waves, TH is thought to increase the J waves and cause fatal arrhythmias, but in this case, rapid cooling with VA-ECMO allowed the patient to successfully complete TH.",

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AU - Sato, Jun

AU - Yagi, Tsukasa

AU - Shimada, Erika

AU - Kobori, Masashi

AU - Watanabe, Kazuhiro

AU - Kuwana, Tsukasa

AU - Chiba, Nobutaka

AU - Saito, Takeshi

AU - Kinoshita, Kosaku

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PY - 2023/12/1

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N2 - A 50-year-old man was admitted to our hospital with hypotension and bradycardia after receiving high doses of atenolol, amlodipine, and etizolam. He had a drug-induced J wave on electrocardiography and subsequently underwent cardiac arrest. The patient was successfully rescued by venoarterial extracorporeal membrane oxygenation (VA-ECMO) and a good neurological outcome was achieved with therapeutic hypothermia (TH). In patients with J waves, TH is thought to increase the J waves and cause fatal arrhythmias, but in this case, rapid cooling with VA-ECMO allowed the patient to successfully complete TH.

AB - A 50-year-old man was admitted to our hospital with hypotension and bradycardia after receiving high doses of atenolol, amlodipine, and etizolam. He had a drug-induced J wave on electrocardiography and subsequently underwent cardiac arrest. The patient was successfully rescued by venoarterial extracorporeal membrane oxygenation (VA-ECMO) and a good neurological outcome was achieved with therapeutic hypothermia (TH). In patients with J waves, TH is thought to increase the J waves and cause fatal arrhythmias, but in this case, rapid cooling with VA-ECMO allowed the patient to successfully complete TH.

KW - J wave

KW - beta-blocker

KW - calcium channel blocker

KW - extracorporeal cardiopulmonary resuscitation

KW - therapeutic hypothermia

UR - https://www.scopus.com/pages/publications/85172297752

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JO - Therapeutic Hypothermia and Temperature Management

JF - Therapeutic Hypothermia and Temperature Management

IS - 4

ER -

Successful Therapeutic Hypothermia in a Patient with Drug-Induced J Waves and Cardiac Arrest: A Case Report

Abstract

Keywords

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