Study of the immunological stress caused by breast surgery methods

Tomohiro Hirano; Kenichi Sakurai; Shigeru Fujisaki; Keita Adachi; Shuhei Suzuki; Yuki Masuo; Saki Nagashima; Yukiko Hara; Katsuhisa Enomoto; Ryouichi Tomita; Kenji Gonda

Study of the immunological stress caused by breast surgery methods

Tomohiro Hirano, Kenichi Sakurai, Shigeru Fujisaki, Keita Adachi, Shuhei Suzuki, Yuki Masuo, Saki Nagashima, Yukiko Hara, Katsuhisa Enomoto, Ryouichi Tomita, Kenji Gonda

School of Medicine

Research output: Contribution to journal › Review article › peer-review

Abstract

To determine the role of immunosuppressive acidic protein (IAP) in the host defense of surgical patients, we investigated the kinetics of the post-operative elevation of IAP, as well as factors influencing the increase in serum IAP concentration, in 17 patients who underwent breast surgery. IAP was not increased in the pre-operation phase, post-operation phase, or 2 weeks after surgery, by various breast surgery methods. In contrast, IL-6 was increased in the post-operation phase by all breast surgery methods. IL-6 correlated with anesthesia time. These results suggest that breast surgical methods are less immunologically invasive than other major surgery.

Original language	English
Pages (from-to)	1274-1276
Number of pages	3
Journal	Japanese Journal of Cancer and Chemotherapy
Volume	43
Issue number	10
Publication status	Published - Oct 2016

Keywords

Breast surgery
Immunosuppressive acidic protein (IAP)
Lnterleukin-6 (IL-6)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "Study of the immunological stress caused by breast surgery methods",

abstract = "To determine the role of immunosuppressive acidic protein (IAP) in the host defense of surgical patients, we investigated the kinetics of the post-operative elevation of IAP, as well as factors influencing the increase in serum IAP concentration, in 17 patients who underwent breast surgery. IAP was not increased in the pre-operation phase, post-operation phase, or 2 weeks after surgery, by various breast surgery methods. In contrast, IL-6 was increased in the post-operation phase by all breast surgery methods. IL-6 correlated with anesthesia time. These results suggest that breast surgical methods are less immunologically invasive than other major surgery.",

keywords = "Breast surgery, Immunosuppressive acidic protein (IAP), Lnterleukin-6 (IL-6)",

author = "Tomohiro Hirano and Kenichi Sakurai and Shigeru Fujisaki and Keita Adachi and Shuhei Suzuki and Yuki Masuo and Saki Nagashima and Yukiko Hara and Katsuhisa Enomoto and Ryouichi Tomita and Kenji Gonda",

year = "2016",

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language = "English",

volume = "43",

pages = "1274--1276",

journal = "Japanese Journal of Cancer and Chemotherapy",

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T1 - Study of the immunological stress caused by breast surgery methods

AU - Hirano, Tomohiro

AU - Sakurai, Kenichi

AU - Fujisaki, Shigeru

AU - Adachi, Keita

AU - Suzuki, Shuhei

AU - Masuo, Yuki

AU - Nagashima, Saki

AU - Hara, Yukiko

AU - Enomoto, Katsuhisa

AU - Tomita, Ryouichi

AU - Gonda, Kenji

PY - 2016/10

Y1 - 2016/10

N2 - To determine the role of immunosuppressive acidic protein (IAP) in the host defense of surgical patients, we investigated the kinetics of the post-operative elevation of IAP, as well as factors influencing the increase in serum IAP concentration, in 17 patients who underwent breast surgery. IAP was not increased in the pre-operation phase, post-operation phase, or 2 weeks after surgery, by various breast surgery methods. In contrast, IL-6 was increased in the post-operation phase by all breast surgery methods. IL-6 correlated with anesthesia time. These results suggest that breast surgical methods are less immunologically invasive than other major surgery.

AB - To determine the role of immunosuppressive acidic protein (IAP) in the host defense of surgical patients, we investigated the kinetics of the post-operative elevation of IAP, as well as factors influencing the increase in serum IAP concentration, in 17 patients who underwent breast surgery. IAP was not increased in the pre-operation phase, post-operation phase, or 2 weeks after surgery, by various breast surgery methods. In contrast, IL-6 was increased in the post-operation phase by all breast surgery methods. IL-6 correlated with anesthesia time. These results suggest that breast surgical methods are less immunologically invasive than other major surgery.

KW - Breast surgery

KW - Immunosuppressive acidic protein (IAP)

KW - Lnterleukin-6 (IL-6)

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M3 - Review article

C2 - 27760958

AN - SCOPUS:85011024616

SN - 0385-0684

VL - 43

SP - 1274

EP - 1276

JO - Japanese Journal of Cancer and Chemotherapy

JF - Japanese Journal of Cancer and Chemotherapy

IS - 10

ER -

Study of the immunological stress caused by breast surgery methods

Abstract

Keywords

UN SDGs

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