Self-completion method of endoscopic submucosal dissection using the Endosaber for treating colorectal neoplasms (with video)

Mitsuru Esaki, Shun Yamakawa, Ryoji Ichijima, Sho Suzuki, Chika Kusano, Hisatomo Ikehara, Yosuke Minoda, Eikichi Ihara, Takuji Gotoda

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)


Endoscopic submucosal dissection (ESD) is effective for the treatment of colorectal neoplasms. We have developed a self-completion ESD (S-ESD) using Endosaber without requiring additional instruments or assistance. This prospective cohort study was conducted to investigate the feasibility of S-ESD for colorectal neoplasms. Patients with colorectal neoplasms measuring 20–40 mm in size were enrolled. A single operator, without assistance, performed ESD using only the Endosaber. The primary outcome was the success rate of S-ESD. Secondary outcomes included procedure time, the rates of en bloc, complete, and curative resection, and complication rates, including the incidence of perforation and delayed bleeding. In total, 15 patients with 15 lesions were enrolled. The median size of the resected lesions was 28 mm (interquartile range 25–29 mm). S-ESD success rate of 100% was achieved. The median procedure time was 44 min (29.5–53.5 min). We observed en bloc, complete, and curative resection rates of 100%, 93.3%, and 86.7%, respectively, and a complication rate of 6.7% (perforation: 0%, delayed bleeding: 6.7%). S-ESD for colorectal neoplasms was successfully performed with favorable treatment outcomes and low complication rates. S-ESD reduces the number of devices and extent of assistance, making S-ESD a simple and cost-effective procedure.

Original languageEnglish
Article number5821
JournalScientific Reports
Issue number1
Publication statusPublished - Dec 2022


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