Progressive diffuse idiopathic spinal hyperostosis: a case report

Koji Matsumoto, Hiroshi Uei, Yasuaki Tokuhashi

Research output: Contribution to journalArticlepeer-review


Diffuse idiopathic spinal hyperostosis (DISH) causes various problems, such as adjacent disc dysfunction, pseudarthrosis, or reossification, when spinal surgery is performed or spinal fracture occurs. The authors herein describe a patient with DISH in whom ossification of the anterior longitudinal ligament progressively advanced from the thoracic to sacral vertebrae during a 14-year period. Surgery was performed three times to treat the characteristic problems associated with DISH: abnormal sagittal alignment of the spine, ossification of the posterior longitudinal ligament, reossification of the laminectomy-treated regions and accompanying spinal canal stenosis, pseudarthrosis after spinal fracture, and delayed palsy. DISH-associated problems after spinal fusion are not rare, but this patient developed a particularly large number of problems often seen in the long term after spinal fusion in patients with DISH. Clinicians must be aware of problems being likely to occur in ossification-discontinuous and fragile regions during the postoperative follow-up.

Original languageEnglish
Pages (from-to)3955-3962
Number of pages8
JournalJournal of International Medical Research
Issue number8
Publication statusPublished - 1 Aug 2019


  • Diffuse idiopathic hyperostosis
  • complication
  • delayed palsy
  • fracture
  • lumbar lordosis
  • lumbar operation
  • ossification of ligament
  • pseudarthrosis
  • sagittal vertical axis
  • thoracic kyphosis


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