Polymicrobial peri-implant infection

Takahiko Shiba, Takayasu Watanabe

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

1 Citation (Scopus)


The human oral cavity is an entrance to the digestive system and provides a habitat for bacteria. A microbiota is formed by a variety of bacterial species on the soft and hard tissues in the oral cavity, and is a community in which bacteria interact with each other. However, among the hundreds of bacterial species within a microbiota, only a limited number of species have been considered to be involved in oral infectious diseases such as dental caries and periodontitis. On the other hand, with the development of next-generation high-throughput sequencing technology, the activities and interactions of multiple bacterial species within a microbiota are being focused on in recent bacteriological research studies. In this chapter, the bacteriological aspect of peri-implantitis will be highlighted, especially with a focus on its polymicrobial nature. We will then present our research for the microbiota in peri-implantitis lesions, and discuss future perspectives of polymicrobial peri-implant infection.

Original languageEnglish
Title of host publicationRisk Factors for Peri-implant Diseases
PublisherSpringer International Publishing
Number of pages11
ISBN (Electronic)9783030391850
ISBN (Print)9783030391843
Publication statusPublished - 1 Jan 2020
Externally publishedYes


  • 16S rRNA
  • Dysbiosis
  • Metatranscriptome
  • Microbiota
  • Network
  • Next-generation sequencer (NGS)
  • Polymicrobial infection


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