Long-term follow-up of a Japanese patient with hepatitis B virus genotype H and human immunodeficiency virus coinfection

Masahiro Ogawa, Shinya Kamimura, Tatsuo Kanda, Hiroshi Takahashi, Taku Mizutani, Naoki Matsumoto, Toshiki Yamamoto, Kazushige Nirei, Shunichi Matsuoka, Masami Takei, Mitsuhiko Moriyama

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Hepatitis B virus (HBV) genotypes affect the pathogenesis of disease progression during the course of HBV infection. In Japan, HBV genotype H is one of the rare HBV genotypes. We recovered HBV genotype H from a blood sample from a Japanese HIV-infected patient with acute exacerbation of chronic HBV infection. Due to the development of drugs for treating HBV and HIV, HBV genotype H and HIV coinfection has been well controlled by nucleos(t)ide analogs and highly active antiretroviral therapy, respectively, from 2002 to 2019. Further study is needed with regard to HBV genotype H and its pathogenesis.

Original languageEnglish
Pages (from-to)633-639
Number of pages7
JournalFuture Virology
Volume14
Issue number10
DOIs
Publication statusPublished - 2019

Keywords

  • HBV
  • HIV
  • Japan
  • genotype H
  • lamivudine
  • long-term observation
  • nucleos(t)ide analogs

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