Abstract
Hepatitis B virus (HBV) genotypes affect the pathogenesis of disease progression during the course of HBV infection. In Japan, HBV genotype H is one of the rare HBV genotypes. We recovered HBV genotype H from a blood sample from a Japanese HIV-infected patient with acute exacerbation of chronic HBV infection. Due to the development of drugs for treating HBV and HIV, HBV genotype H and HIV coinfection has been well controlled by nucleos(t)ide analogs and highly active antiretroviral therapy, respectively, from 2002 to 2019. Further study is needed with regard to HBV genotype H and its pathogenesis.
Original language | English |
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Pages (from-to) | 633-639 |
Number of pages | 7 |
Journal | Future Virology |
Volume | 14 |
Issue number | 10 |
DOIs | |
Publication status | Published - 2019 |
Keywords
- HBV
- HIV
- Japan
- genotype H
- lamivudine
- long-term observation
- nucleos(t)ide analogs