Impact of the COVID-19 outbreak on hospitalizations and outcomes in patients with acute myocardial infarction in a Japanese Single Center

Riku Arai, Daisuke Fukamachi, Yasunari Ebuchi, Suguru Migita, Tomoyuki Morikawa, Masaki Monden, Norio Takei, Takehiro Tamaki, Keisuke Kojima, Naotaka Akutsu, Nobuhiro Murata, Daisuke Kitano, Yasuo Okumura

Research output: Contribution to journalArticlepeer-review

7 Citations (Scopus)

Abstract

There are a few Japanese data regarding the incidence and outcomes of acute myocardial infarction (AMI) after the coronavirus disease 2019 (COVID-19) outbreak. We retrospectively reviewed the data of AMI patients admitted to the Nihon University Itabashi Hospital after a COVID-19 outbreak in 2020 (COVID-19 period) and the same period from 2017 to 2019 (control period). The patients’ characteristics, time course of admission, diagnosis, and treatment of AMI, and 30-day mortality were compared between the two period-groups for both ST-segment elevation myocardial infarction (STEMI) and non-STEMI (NSTEMI), respectively. The AMI inpatients decreased by 5.7% after the COVID-19 outbreak. There were no differences among most patient backgrounds between the two-period groups. For NSTEMI, the time from the symptom onset to admission was significantly longer, and that from the AMI diagnosis to the catheter examination tended to be longer during the COVID-19 period than the control period, but not for STEMI. The 30-day mortality was significantly higher during the COVID-19 period for NSTEMI (23.1% vs. 1.9%, P = 0.004), but not for STEMI (9.4% vs. 8.3%, P = 0.77). In conclusion, hospitalizations for AMI decreased after the COVID-19 outbreak. Acute cardiac care for STEMI and the associated outcome did not change, but NSTEMI outcome worsened after the COVID-19 outbreak, which may have been associated with delayed medical treatment due to the indirect impact of the COVID-19 pandemic.

Original languageEnglish
Pages (from-to)1474-1483
Number of pages10
JournalHeart and Vessels
Volume36
Issue number10
DOIs
Publication statusPublished - Oct 2021

Keywords

  • Acute myocardial infarction
  • COVID-19 outbreak
  • Time from the symptom onset to admission

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