Evaluation of COPD's diaphragm motion extracted from 4D-MRI

Windra Swastika, Yoshitada Masuda, Naoko Kawata, Koji Matsumoto, Toshio Suzuki, Ken Iesato, Yuji Tada, Toshihiko Sugiura, Nobuhiro Tanabe, Koichiro Tatsumi, Takashi Ohnishi, Hideaki Haneishi

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Citation (Scopus)

Abstract

We have developed a method called intersection profile method to construct a 4D-MRI (3D+time) from time-series of 2D-MRI. The basic idea is to find the best matching of the intersection profile from the time series of 2D-MRI in sagittal plane (navigator slice) and time series of 2D-MRI in coronal plane (data slice). In this study, we use 4D-MRI to semiautomatically extract the right diaphragm motion of 16 subjects (8 healthy subjects and 8 COPD patients). The diaphragm motion is then evaluated quantitatively by calculating the displacement of each subjects and normalized it. We also generate phase-length map to view and locate paradoxical motion of the COPD patients. The quantitative results of the normalized displacement shows that COPD patients tend to have smaller displacement compared to healthy subjects. The average normalized displacement of total 8 COPD patients is 9.4mm and the average of normalized displacement of 8 healthy volunteers is 15.3mm. The generated phase-length maps show that not all of the COPD patients have paradoxical motion, however if it has paradoxical motion, the phase-length map is able to locate where does it occur.

Original languageEnglish
Title of host publicationMedical Imaging 2015
Subtitle of host publicationImage Processing
EditorsMartin A. Styner, Sebastien Ourselin
PublisherSPIE
ISBN (Electronic)9781628415032
DOIs
Publication statusPublished - 2015
Externally publishedYes
EventMedical Imaging 2015: Image Processing - Orlando, United States
Duration: 24 Feb 201526 Feb 2015

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9413
ISSN (Print)1605-7422

Conference

ConferenceMedical Imaging 2015: Image Processing
Country/TerritoryUnited States
CityOrlando
Period24/02/1526/02/15

Keywords

  • 4D-MRI
  • COPD
  • diaphragm motion

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