Endoscopic photodynamic therapy using talaporfin sodium for recurrent intranasal carcinomas after radiotherapy in three dogs

K. Ishigaki; K. Nariai; M. Izumi; K. Teshima; M. Seki; K. Edamura; T. Takahashi; K. Asano

doi:10.1111/jsap.12667

Endoscopic photodynamic therapy using talaporfin sodium for recurrent intranasal carcinomas after radiotherapy in three dogs

K. Ishigaki, K. Nariai, M. Izumi, K. Teshima, M. Seki, K. Edamura, T. Takahashi, K. Asano

College of Bioresource Sciences

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Radiation is the treatment of choice for canine nasal tumours but, in almost all cases, there is local recurrence associated with poor prognosis. This report describes the effect of endoscopic photodynamic therapy using talaporfin sodium for canine intranasal carcinoma recurring after radiation therapy. Rhinoscopic photodynamic therapy was administered after radiation therapy in three dogs with recurrent intranasal carcinoma. Two to 24 illuminations of a 665-nm diode laser were performed two hours after intravenous bolus injection of 5·0 mg/kg of talaporfin sodium. Photodynamic therapy induced almost complete remission and prolonged survival time in all cases suggesting that it might be a useful treatment for intranasal carcinomas that recur after radiation.

Original language	English
Pages (from-to)	128-132
Number of pages	5
Journal	Journal of Small Animal Practice
Volume	59
Issue number	2
DOIs	https://doi.org/10.1111/jsap.12667
Publication status	Published - 1 Feb 2018

Access to Document

10.1111/jsap.12667

Cite this

@article{ee6dc6adb58e4d8e866580197b5ee9b4,

title = "Endoscopic photodynamic therapy using talaporfin sodium for recurrent intranasal carcinomas after radiotherapy in three dogs",

abstract = "Radiation is the treatment of choice for canine nasal tumours but, in almost all cases, there is local recurrence associated with poor prognosis. This report describes the effect of endoscopic photodynamic therapy using talaporfin sodium for canine intranasal carcinoma recurring after radiation therapy. Rhinoscopic photodynamic therapy was administered after radiation therapy in three dogs with recurrent intranasal carcinoma. Two to 24 illuminations of a 665-nm diode laser were performed two hours after intravenous bolus injection of 5·0 mg/kg of talaporfin sodium. Photodynamic therapy induced almost complete remission and prolonged survival time in all cases suggesting that it might be a useful treatment for intranasal carcinomas that recur after radiation.",

author = "K. Ishigaki and K. Nariai and M. Izumi and K. Teshima and M. Seki and K. Edamura and T. Takahashi and K. Asano",

note = "Publisher Copyright: {\textcopyright} 2017 British Small Animal Veterinary Association",

year = "2018",

month = feb,

day = "1",

doi = "10.1111/jsap.12667",

language = "English",

volume = "59",

pages = "128--132",

journal = "Journal of Small Animal Practice",

issn = "0022-4510",

publisher = "Wiley-Blackwell",

number = "2",

}

TY - JOUR

T1 - Endoscopic photodynamic therapy using talaporfin sodium for recurrent intranasal carcinomas after radiotherapy in three dogs

AU - Ishigaki, K.

AU - Nariai, K.

AU - Izumi, M.

AU - Teshima, K.

AU - Seki, M.

AU - Edamura, K.

AU - Takahashi, T.

AU - Asano, K.

PY - 2018/2/1

Y1 - 2018/2/1

N2 - Radiation is the treatment of choice for canine nasal tumours but, in almost all cases, there is local recurrence associated with poor prognosis. This report describes the effect of endoscopic photodynamic therapy using talaporfin sodium for canine intranasal carcinoma recurring after radiation therapy. Rhinoscopic photodynamic therapy was administered after radiation therapy in three dogs with recurrent intranasal carcinoma. Two to 24 illuminations of a 665-nm diode laser were performed two hours after intravenous bolus injection of 5·0 mg/kg of talaporfin sodium. Photodynamic therapy induced almost complete remission and prolonged survival time in all cases suggesting that it might be a useful treatment for intranasal carcinomas that recur after radiation.

AB - Radiation is the treatment of choice for canine nasal tumours but, in almost all cases, there is local recurrence associated with poor prognosis. This report describes the effect of endoscopic photodynamic therapy using talaporfin sodium for canine intranasal carcinoma recurring after radiation therapy. Rhinoscopic photodynamic therapy was administered after radiation therapy in three dogs with recurrent intranasal carcinoma. Two to 24 illuminations of a 665-nm diode laser were performed two hours after intravenous bolus injection of 5·0 mg/kg of talaporfin sodium. Photodynamic therapy induced almost complete remission and prolonged survival time in all cases suggesting that it might be a useful treatment for intranasal carcinomas that recur after radiation.

UR - http://www.scopus.com/inward/record.url?scp=85017338225&partnerID=8YFLogxK

U2 - 10.1111/jsap.12667

DO - 10.1111/jsap.12667

M3 - Article

C2 - 28369945

AN - SCOPUS:85017338225

SN - 0022-4510

VL - 59

SP - 128

EP - 132

JO - Journal of Small Animal Practice

JF - Journal of Small Animal Practice

IS - 2

ER -

Endoscopic photodynamic therapy using talaporfin sodium for recurrent intranasal carcinomas after radiotherapy in three dogs

Abstract

Access to Document

Other files and links

Fingerprint

Cite this