Endoscopic biliary drainage using a 4-Fr catheter for biliary obstruction: a pilot study

Noriyuki Kuniyoshi, Hiroo Imazu, Shuzo Nomura, Suguru Hamana, Rota Osawa, Kouji Yamada, Mariko Fujisawa, Mitsuhiko Moriyama

Research output: Contribution to journalArticlepeer-review


Introduction: Stent or endoscopic nasobiliary drainage (ENBD) catheter placement for a tight, complicated biliary stricture is still technically challenging. A thin, 4-Fr ENBD catheter (4-Fr catheter) has been developed to overcome this difficulty. The study aimed to evaluate the feasibility of the 4-Fr catheter for endoscopic biliary drainage (EBD). Material and methods: We performed a retrospective review of 51 patients who underwent EBD with the 4-Fr catheter because placement of a conventional drainage catheter (CDC) had failed. Results: The success rate of 4-Fr catheter placement was 96.1% (49/51). The median patency period of the catheter was 114 days (95% CI, 53–200). Among the 49 patients with successful placement of the catheter, adverse events occurred in five (10.2%) patients: post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP), two patients; catheter dislocation, one patient; and kinking of the 4-Fr catheter, two patients. Both cases of PEP improved with conservative treatment, but all cases of catheter dislocation and kinking required reintervention with a 4-Fr catheter. Forty-three (87.8%) patients achieved clinical remission after EBD with a 4-Fr catheter. Conclusions: The newly developed 4-Fr catheter is safe and feasible for EBD in patients in whom CDC placement is difficult due to a tight, complicated biliary stricture.

Original languageEnglish
Pages (from-to)1035-1040
Number of pages6
JournalMinimally Invasive Therapy and Allied Technologies
Issue number7
Publication statusPublished - 2022


  • 4-Fr catheter
  • Endoscopic biliary drainage
  • endoscopic biliary stenting
  • endoscopic nasobiliary drainage
  • tight biliary strictures


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