Effect of denture adhesives on masticatory performance: Multicenter randomized controlled trial

Suguru Kimoto, Yasuhiko Kawai, Asako Suzuki, Yasuyo Koide, Hisatomo Kondo, Taro Nomura, Akito Tsuboi, Yoshihiko Ito, Guang Hong, Shunsuke Minakuchi, Gaku Ohwada, Yusuke Sato, Tetsuya Suzuki, Katsuhiko Kimoto, Makiko Saita, Noriyuki Hoshi, Yoshikazu Yoneyama, Yohei Sato, Masakazu Morokuma, Joji OkazakiTakeshi Maeda, Kenichiro Nakai, Tetsuo Ichikawa, Kan Nagao, Keiko Fujimoto, Tadafumi Kurogi, Hiroshi Murata, Hitomi Okazaki, Masahiro Nishimura, Yasuhiro Nishi, Mamoru Murakami, Toshio Hosoi, Taizo Hamada

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

Purpose: The purpose of this study is to investigate the effects of denture adhesives on masticatory performance via a 10-center, parallel, randomized, controlled trial of complete denture wearers in Japan. Methods: The trial was conducted between September 2013 and October 2016. The inclusion criteria were complete edentulism, willingness to undergo new complete denture treatment, and willingness to return for recall treatment. The exclusion criteria were age 90 years or older, presence of severe systemic illness, inability to understand the question-naires, wearing metal base complete dentures, denture adhesive user, wearing prosthetics for maxillofacial defects, wearing complete dentures with tissue conditioners, and severe xerostomia. Randomization of the powder-type denture adhesive (powder), cream-type denture adhesive (cream), and control (saline) groups was performed using a sealed en-velope system. Masticatory performance was measured using color-changeable chewing gum. Intervention blinding was not feasible. Results: Sixty-seven control, 69 powder, and 64 cream participants are analyzed using the intention-to-treat principle. The participants in all groups show significantly improved masticatory performance at post-intervention (paired t-test with Bonferroni correction P < 0.0001). However, no significant difference in masticatory performance is detected among the three groups (one-way analysis of variance). A significant negative correlation between pre-and post-changes in mastica-tory performance and intraoral condition scores is observed (Pearson’s correlation coefficient, P < 0.0001). Conclusions: Although denture adhesives improved the masticatory performance of complete denture wearers, their clinical effects are comparable to those of saline solution. The use of denture adhesives is more effective in complete denture wearers with unsatisfactory intraoral conditions.

Original languageEnglish
Pages (from-to)132-138
Number of pages7
JournalJournal of Prosthodontic Research
Volume68
Issue number1
DOIs
Publication statusPublished - 2024

Keywords

  • Complete denture
  • Denture adhesive
  • Masticatory performance
  • Multicenter study
  • Randomized controlled clinical trial

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