Direct molecular evidence for both multicentric and monoclonal carcinogenesis followed by transdifferentiation from hepatocellular carcinoma to cholangiocarcinoma in a case of metachronous liver cancer

Sumie Ohni, Hiromi Yamaguchi, Yukari Hirotani, Yoko Nakanishi, Yutaka Midorikawa, Masahiko Sugitani, Hiromu Naruse, Tomohiro Nakayama, Makoto Makishima, Mariko Esumi

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Biochemistry, Genetics and Molecular Biology

Medicine and Dentistry