Diffusion-weighted magnetic resonance imaging of parotid glands in diabetes mellitus: A preliminary study

Hirotaka Muraoka; Takashi Kaneda; Takumi Kondo; Shunya Okada; Eri Sawada; Satoshi Tokunaga

doi:10.1002/osi2.1192

Diffusion-weighted magnetic resonance imaging of parotid glands in diabetes mellitus: A preliminary study

Hirotaka Muraoka, Takashi Kaneda, Takumi Kondo, Shunya Okada, Eri Sawada, Satoshi Tokunaga

School of Dentistry at Matsudo

Nihon University

Research output: Contribution to journal › Article › peer-review

Abstract

Objective: This retrospective study aimed to assess the parotid glands in diabetes mellitus (DM) using diffusion-weighted magnetic resonance imaging (DW-MRI). Methods: We investigated 54 patients aged between 38 and 83 years, with DM (DM group) and without DM (control group), who underwent magnetic resonance imaging (MRI) in the facility between November 2006 and January 2021. We calculated the median apparent diffusion coefficients (ADCs) of the parotid glands in the control group and DM group. These groups were compared using the Mann–Whitney U tests. A receiver operating characteristic (ROC) curve analysis was performed to assess the ability of the ADC to predict DM. Statistical significance was set at p < 0.05. Results: The median ADCs of parotid grands in the control group and DM group were 0.83 × 10⁻³ mm²/s and 0.74 × 10⁻³ mm²/s, respectively (p < 0.01). ROC analysis revealed a cut-off ADC value of 0.81 to distinguish between the control and DM group. Sensitivity, specificity, accuracy, and area under the ROC curve were 0.7, 0.67, 0.69, and 0.71, respectively. Conclusion: The ADC was significantly higher in DM groups than in the control group. This suggests that DW-MRI may be able to quantitatively distinguish parotid glands between normal and DM patients.

Original language	English
Pages (from-to)	106-111
Number of pages	6
Journal	Oral Science International
Volume	21
Issue number	1
DOIs	https://doi.org/10.1002/osi2.1192
Publication status	Published - Jan 2024

Keywords

apparent diffusion coefficient
diabetes mellitus
diffusion-weighted imaging
magnetic resonance imaging
salivary glands

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10.1002/osi2.1192

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title = "Diffusion-weighted magnetic resonance imaging of parotid glands in diabetes mellitus: A preliminary study",

abstract = "Objective: This retrospective study aimed to assess the parotid glands in diabetes mellitus (DM) using diffusion-weighted magnetic resonance imaging (DW-MRI). Methods: We investigated 54 patients aged between 38 and 83 years, with DM (DM group) and without DM (control group), who underwent magnetic resonance imaging (MRI) in the facility between November 2006 and January 2021. We calculated the median apparent diffusion coefficients (ADCs) of the parotid glands in the control group and DM group. These groups were compared using the Mann–Whitney U tests. A receiver operating characteristic (ROC) curve analysis was performed to assess the ability of the ADC to predict DM. Statistical significance was set at p < 0.05. Results: The median ADCs of parotid grands in the control group and DM group were 0.83 × 10−3 mm2/s and 0.74 × 10−3 mm2/s, respectively (p < 0.01). ROC analysis revealed a cut-off ADC value of 0.81 to distinguish between the control and DM group. Sensitivity, specificity, accuracy, and area under the ROC curve were 0.7, 0.67, 0.69, and 0.71, respectively. Conclusion: The ADC was significantly higher in DM groups than in the control group. This suggests that DW-MRI may be able to quantitatively distinguish parotid glands between normal and DM patients.",

keywords = "apparent diffusion coefficient, diabetes mellitus, diffusion-weighted imaging, magnetic resonance imaging, salivary glands",

author = "Hirotaka Muraoka and Takashi Kaneda and Takumi Kondo and Shunya Okada and Eri Sawada and Satoshi Tokunaga",

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year = "2024",

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doi = "10.1002/osi2.1192",

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T2 - A preliminary study

AU - Muraoka, Hirotaka

AU - Kaneda, Takashi

AU - Kondo, Takumi

AU - Okada, Shunya

AU - Sawada, Eri

AU - Tokunaga, Satoshi

PY - 2024/1

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N2 - Objective: This retrospective study aimed to assess the parotid glands in diabetes mellitus (DM) using diffusion-weighted magnetic resonance imaging (DW-MRI). Methods: We investigated 54 patients aged between 38 and 83 years, with DM (DM group) and without DM (control group), who underwent magnetic resonance imaging (MRI) in the facility between November 2006 and January 2021. We calculated the median apparent diffusion coefficients (ADCs) of the parotid glands in the control group and DM group. These groups were compared using the Mann–Whitney U tests. A receiver operating characteristic (ROC) curve analysis was performed to assess the ability of the ADC to predict DM. Statistical significance was set at p < 0.05. Results: The median ADCs of parotid grands in the control group and DM group were 0.83 × 10−3 mm2/s and 0.74 × 10−3 mm2/s, respectively (p < 0.01). ROC analysis revealed a cut-off ADC value of 0.81 to distinguish between the control and DM group. Sensitivity, specificity, accuracy, and area under the ROC curve were 0.7, 0.67, 0.69, and 0.71, respectively. Conclusion: The ADC was significantly higher in DM groups than in the control group. This suggests that DW-MRI may be able to quantitatively distinguish parotid glands between normal and DM patients.

AB - Objective: This retrospective study aimed to assess the parotid glands in diabetes mellitus (DM) using diffusion-weighted magnetic resonance imaging (DW-MRI). Methods: We investigated 54 patients aged between 38 and 83 years, with DM (DM group) and without DM (control group), who underwent magnetic resonance imaging (MRI) in the facility between November 2006 and January 2021. We calculated the median apparent diffusion coefficients (ADCs) of the parotid glands in the control group and DM group. These groups were compared using the Mann–Whitney U tests. A receiver operating characteristic (ROC) curve analysis was performed to assess the ability of the ADC to predict DM. Statistical significance was set at p < 0.05. Results: The median ADCs of parotid grands in the control group and DM group were 0.83 × 10−3 mm2/s and 0.74 × 10−3 mm2/s, respectively (p < 0.01). ROC analysis revealed a cut-off ADC value of 0.81 to distinguish between the control and DM group. Sensitivity, specificity, accuracy, and area under the ROC curve were 0.7, 0.67, 0.69, and 0.71, respectively. Conclusion: The ADC was significantly higher in DM groups than in the control group. This suggests that DW-MRI may be able to quantitatively distinguish parotid glands between normal and DM patients.

KW - apparent diffusion coefficient

KW - diabetes mellitus

KW - diffusion-weighted imaging

KW - magnetic resonance imaging

KW - salivary glands

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Diffusion-weighted magnetic resonance imaging of parotid glands in diabetes mellitus: A preliminary study

Abstract

Keywords

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