Diagnostic ability of high-definition imaging using ultraslim endoscopes in early gastric cancer

Tomomi Sugita, Sho Suzuki, Ryoji Ichijima, Kanako Ogura, Chika Kusano, Hisatomo Ikehara, Takuji Gotoda, Mitsuhiko Moriyama

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Purpose: It is unclear whether high-definition (HD) imaging improves visibility and diagnostic ability in early gastric cancer (EGC) compared with standard-definition (SD) imaging. We aimed to compare the diagnostic performance and visibility scores of HD and SD ultraslim endoscopes in EGC. Materials and Methods: We used HD and SD ultraslim endoscopes to obtain 60 images with similar compositions of gastric environments. Of the 60 images, 30 showed EGC (15 images for each modality) and 30 showed no EGC (15 images for each modality). Seventeen endoscopists evaluated the presence and location of the lesions in each image. Diagnostic ability was compared between modalities. The color difference between a lesion and the surrounding mucosa (ΔE) was measured and compared between the modalities. Results: The ability of HD to detect EGC was significantly higher than that of SD (accuracy: 80.8% vs. 71.6%, P=0.017; sensitivity: 94.9% vs. 76.5%, P<0.001; positive predictive value, 76.2% vs. 55.3%, P<0.001; and negative predictive value (NPV), 94.1% vs. 73.5%, P<0.001). The ability of HD to determine the horizontal extent of EGC was significantly higher than that of SD (accuracy: 71.0% vs. 57.8%, P=0.004; sensitivity: 75.3% vs. 49.0%, P<0.001; NPV, 72.9% vs. 55.9%, P<0.001; and area under the curve: 0.891 vs. 0.631, P=0.038). The mean ΔE was significantly higher for HD than for SD (10.3 vs. 5.9, P=0.011). Conclusions: The HD ultraslim endoscope showed a higher diagnostic performance in EGC than the SD endoscope because it provided good color contrast.

Original languageEnglish
Pages (from-to)246-257
Number of pages12
JournalJournal of Gastric Cancer
Volume21
Issue number3
DOIs
Publication statusPublished - 1 Sept 2021

Keywords

  • Diagnosis
  • Diagnostic imaging
  • Endoscopy
  • Gastric cancer
  • Screening

Fingerprint

Dive into the research topics of 'Diagnostic ability of high-definition imaging using ultraslim endoscopes in early gastric cancer'. Together they form a unique fingerprint.

Cite this