TY - JOUR
T1 - Developing odontoma (ameloblastic fibro-odontoma) of the mandible
T2 - Report of a case with radiological, histopathological and immunohistochemical studies
AU - Imaoka, Saya
AU - Moriyama, Ayuko
AU - Shiratsuchi, Hiroshi
AU - Tamagawa, Takaaki
AU - Asano, Masatake
N1 - Publisher Copyright:
© 2023 Asian AOMS, ASOMP, JSOP, JSOMS, JSOM, and JAMI
PY - 2024/7
Y1 - 2024/7
N2 - We report a case of ameloblastic fibro-odontoma (AFO) in the second molar region of the left mandible of an 8-year-old girl. Cone beam computed tomography revealed a spatial relationship between the lesion and the gubernaculum tract of an unerupted second molar. Histologically, characteristic multinodular growth of discrete tooth germ-like structures supported the non-neoplastic hamartomatous nature of the lesion. The pattern and degree of syndecan-1 and D2-40 immunoexpression in the epithelial component varied, probably reflecting different stages of maturation. In view of the patient's age (<13 years) and the size of the lesion (<2 cm), the present AFO was likely a developing odontoma.
AB - We report a case of ameloblastic fibro-odontoma (AFO) in the second molar region of the left mandible of an 8-year-old girl. Cone beam computed tomography revealed a spatial relationship between the lesion and the gubernaculum tract of an unerupted second molar. Histologically, characteristic multinodular growth of discrete tooth germ-like structures supported the non-neoplastic hamartomatous nature of the lesion. The pattern and degree of syndecan-1 and D2-40 immunoexpression in the epithelial component varied, probably reflecting different stages of maturation. In view of the patient's age (<13 years) and the size of the lesion (<2 cm), the present AFO was likely a developing odontoma.
KW - Ameloblastic fibro-odontoma
KW - CBCT
KW - Developing odontoma
KW - Gubernaculum tract
UR - http://www.scopus.com/inward/record.url?scp=85178377615&partnerID=8YFLogxK
U2 - 10.1016/j.ajoms.2023.11.004
DO - 10.1016/j.ajoms.2023.11.004
M3 - Article
AN - SCOPUS:85178377615
SN - 2212-5558
VL - 36
SP - 648
EP - 651
JO - Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
JF - Journal of Oral and Maxillofacial Surgery, Medicine, and Pathology
IS - 4
ER -