Abstract
Background: Fatty acid metabolism has a close relationship with metabolic syndrome. Saturated very long-chain fatty acid (hexacosanoic acid; C26:0) was recently reported to be associated with cardiovascular risk factors in adults. Methods: Eighty-eight children (47 male, 41 female; average age, 10.9 y) participated in this study. Concentrations of C26:0 in whole blood were measured. Results: Compared with reported concentrations in the whole blood of adults, children had lower C26:0 concentrations, which had a close relationship with abdominal obesity, increased concentrations of low-density lipoprotein cholesterol and high blood pressure. C26:0 concentrations increased with increasing number of risk factors. Conclusions: Elevation of C26:0 concentrations may be one of the metabolic features of children with cardiovascular risk factors.
| Original language | English |
|---|---|
| Pages (from-to) | 141-143 |
| Number of pages | 3 |
| Journal | Clinica Chimica Acta |
| Volume | 401 |
| Issue number | 1-2 |
| DOIs | |
| Publication status | Published - Mar 2009 |
Keywords
- Abdominal obesity
- Childhood obesity
- Hexacosanoic acid(C26:0)
- Very long-chain fatty acid
