Cardiac MR imaging of hypertrophic cardiomyopathy: Techniques, findings, and clinical relevance

Yasuo Amano, Mitsunobu Kitamura, Hitoshi Takano, Fumi Yanagisawa, Masaki Tachi, Yasuyuki Suzuki, Shinichiro Kumita, Morimasa Takayama

Research output: Contribution to journalReview articlepeer-review

37 Citations (Scopus)

Abstract

Hypertrophic cardiomyopathy (HCM) is a relatively common myocardial genetic disease having a wide variety of symptoms and prognoses. The most serious complications of HCM are sudden cardiac death induced by ventricular arrhythmia or inappropriate changes in blood pressure, and heart failure. Cardiac MR imaging is a valuable imaging method for detecting HCM because of its accurate measurement of wall thickness and myocardial mass without limited view and the unique ability of late gadolinium enhancement (LGE) to identify myocardial fibrosis related to the prognosis of HCM. Tagging and T1 or T2 mapping MR imaging techniques have emerged as quantitative methods for the evaluation of disease severity. In this review, we introduce the MR imaging techniques applied to HCM and demonstrate the typical phenotypes and some morphological characteristics of HCM. In addition, we discuss the clinical relevance of MR imaging for risk stratification and management of HCM.

Original languageEnglish
Pages (from-to)120-131
Number of pages12
JournalMagnetic Resonance in Medical Sciences
Volume17
Issue number2
DOIs
Publication statusPublished - 2018

Keywords

  • Cardiac magnetic resonance imaging
  • Hypertrophic cardiomyopathy
  • Late gadolinium enhancement
  • Steady-state free precession

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