Acute esophageal necrosis after cellulitis in an obese patient with diabetes mellitus

Sho Tanaka, Midori Fujishiro, Ryoji Ichijima, Genta Kohno, Masanori Abe, Hisamitsu Ishihara

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


A 59-year-old obese Japanese man with poorly controlled type 2 diabetes mellitus presented with severe heartburn for 3 days after inguinal cellulitis and exacerbated glycemic control, without any signs of upper gastrointestinal bleeding. The patient had a high plasma glucose level (34.0 mmol/L) and was dehydrated. Emergent esophagogastroduodenoscopy showed black discoloration predominantly affecting the lower esophagus; thus, acute esophageal necrosis (AEN) was diagnosed. This black discoloration was not present on esophagogastroduodenoscopy 20 days prior to presentation, and disappeared 6 days after conservative treatment. To conclude, acute esophageal necrosis should be considered if a patient in marked hyperglycemic status presents with unendurable heartburn, even when upper gastrointestinal bleeding is not observed or recent esophagogastroduodenoscopy was unremarkable.

Original languageEnglish
Pages (from-to)250-252
Number of pages3
JournalJournal of Diabetes Investigation
Issue number1
Publication statusPublished - 1 Jan 2020


  • Diabetes mellitus
  • Endoscopy
  • Esophagitis


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