A Case Report of Changes in Regional Cortical Blood Volume and Oxygenation During Induction of General Anaesthesia with Sevoflurane Versus Propofol in a Paediatric Moyamoya Disease, Evaluated by Near-Infrared Spectroscopy

Noriya Hirose, Yuko Tomita, Miki Matsui, Miho Kijima, Takeshi Maeda, Takahiro Suzuki

Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

Abstract

A safe induction method of general anaesthesia for paediatric moyamoya disease patients has not been fully established. We had the opportunity to administer general anaesthesia twice to a two-year-old girl diagnosed with moyamoya disease. We used different induction methods for general anaesthesia at each session, i.e. slow induction with sevoflurane and rapid induction with propofol, and were able to evaluate changes in her left regional cortical blood volume (rCBV) and oxygenation (rCBO) during both anaesthesia inductions using near-infrared spectroscopy (NIRS). The mean change value of total-Hb (rCBV) (mean ± SD; μmol/L) in the rapid induction was lower than that in the slow induction (−0.54 ± 1.43 vs. 1.82 ± 1.74). However, the TOI (rCBO) levels during both anaesthesia inductions were constantly higher than these respective baseline values (64% in the slow induction, 71% in the rapid induction), and these mean change values in each of the anaesthesia induction were about the same. The present results suggested that both the slow induction method with sevoflurane and the rapid induction method with propofol might be safe and effective for anaesthesia induction in paediatric patients with moyamoya disease.

Original languageEnglish
Title of host publicationAdvances in Experimental Medicine and Biology
PublisherSpringer
Pages51-55
Number of pages5
DOIs
Publication statusPublished - 2024

Publication series

NameAdvances in Experimental Medicine and Biology
Volume1463
ISSN (Print)0065-2598
ISSN (Electronic)2214-8019

Keywords

  • Anaesthesia induction
  • Cortical circulation
  • General anaesthesia
  • Near-infrared spectroscopy
  • Paediatric moyamoya disease

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