A case of an elderly individual with breast cancer diagnosed as Paget's disease after mastectomy

Hitomi Kubota; Yuna Suzuki; Keita Adachi; Shuhei Suzuki; Yukiko Hara; Shigeru Fujisaki; Makoto Makishima; Reina Saga; Tomohiro Hirano; Kenichi Sakurai

A case of an elderly individual with breast cancer diagnosed as Paget's disease after mastectomy

Hitomi Kubota
, Yuna Suzuki
, Keita Adachi
, Shuhei Suzuki
, Yukiko Hara
, Shigeru Fujisaki
, Makoto Makishima
, Reina Saga
, Tomohiro Hirano
, Kenichi Sakurai

School of Medicine

Research output: Contribution to journal › Review article › peer-review

Abstract

We report here a case of a 78-year-old woman, who underwent mastectomy for breast cancer. Mammography showed a mass in the right MO area with an unclear boundary. Ultrasound examination revealed an irregular mass of 40×29×19 mm in the right C region. Dynamic contrast-enhanced MRI showed a 34 mm tumor with contrast effect in the C area of the right breast. We performed a core needle biopsy on the mass, and the histopathological diagnosis was apocrine carcinoma (ER-, PgR-, HER2 3+, and Ki-67 30%) of clinical T2N0M0, stage HA. Right mastectomy and sentinel lymph node biopsy were performed. In the postoperative pathological examination, the main lesion was apocrine carcinoma (ER-, PgR-, HER2 3+, Ki-67 20%) and Paget's disease (ER-, PgR-, HER2 3+, Ki-67 30%). After surgery, the patient was given trastuzumab therapy.

Original language	English
Pages (from-to)	814-816
Number of pages	3
Journal	Japanese Journal of Cancer and Chemotherapy
Volume	46
Issue number	4
Publication status	Published - Apr 2019

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Cite this

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title = "A case of an elderly individual with breast cancer diagnosed as Paget's disease after mastectomy",

abstract = "We report here a case of a 78-year-old woman, who underwent mastectomy for breast cancer. Mammography showed a mass in the right MO area with an unclear boundary. Ultrasound examination revealed an irregular mass of 40×29×19 mm in the right C region. Dynamic contrast-enhanced MRI showed a 34 mm tumor with contrast effect in the C area of the right breast. We performed a core needle biopsy on the mass, and the histopathological diagnosis was apocrine carcinoma (ER-, PgR-, HER2 3+, and Ki-67 30\%) of clinical T2N0M0, stage HA. Right mastectomy and sentinel lymph node biopsy were performed. In the postoperative pathological examination, the main lesion was apocrine carcinoma (ER-, PgR-, HER2 3+, Ki-67 20\%) and Paget's disease (ER-, PgR-, HER2 3+, Ki-67 30\%). After surgery, the patient was given trastuzumab therapy.",

author = "Hitomi Kubota and Yuna Suzuki and Keita Adachi and Shuhei Suzuki and Yukiko Hara and Shigeru Fujisaki and Makoto Makishima and Reina Saga and Tomohiro Hirano and Kenichi Sakurai",

year = "2019",

month = apr,

language = "English",

volume = "46",

pages = "814--816",

journal = "Japanese Journal of Cancer and Chemotherapy",

issn = "0385-0684",

publisher = "Japanese Journal of Cancer and Chemotherapy Publishers Inc.",

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TY - JOUR

T1 - A case of an elderly individual with breast cancer diagnosed as Paget's disease after mastectomy

AU - Kubota, Hitomi

AU - Suzuki, Yuna

AU - Adachi, Keita

AU - Suzuki, Shuhei

AU - Hara, Yukiko

AU - Fujisaki, Shigeru

AU - Makishima, Makoto

AU - Saga, Reina

AU - Hirano, Tomohiro

AU - Sakurai, Kenichi

PY - 2019/4

Y1 - 2019/4

N2 - We report here a case of a 78-year-old woman, who underwent mastectomy for breast cancer. Mammography showed a mass in the right MO area with an unclear boundary. Ultrasound examination revealed an irregular mass of 40×29×19 mm in the right C region. Dynamic contrast-enhanced MRI showed a 34 mm tumor with contrast effect in the C area of the right breast. We performed a core needle biopsy on the mass, and the histopathological diagnosis was apocrine carcinoma (ER-, PgR-, HER2 3+, and Ki-67 30%) of clinical T2N0M0, stage HA. Right mastectomy and sentinel lymph node biopsy were performed. In the postoperative pathological examination, the main lesion was apocrine carcinoma (ER-, PgR-, HER2 3+, Ki-67 20%) and Paget's disease (ER-, PgR-, HER2 3+, Ki-67 30%). After surgery, the patient was given trastuzumab therapy.

AB - We report here a case of a 78-year-old woman, who underwent mastectomy for breast cancer. Mammography showed a mass in the right MO area with an unclear boundary. Ultrasound examination revealed an irregular mass of 40×29×19 mm in the right C region. Dynamic contrast-enhanced MRI showed a 34 mm tumor with contrast effect in the C area of the right breast. We performed a core needle biopsy on the mass, and the histopathological diagnosis was apocrine carcinoma (ER-, PgR-, HER2 3+, and Ki-67 30%) of clinical T2N0M0, stage HA. Right mastectomy and sentinel lymph node biopsy were performed. In the postoperative pathological examination, the main lesion was apocrine carcinoma (ER-, PgR-, HER2 3+, Ki-67 20%) and Paget's disease (ER-, PgR-, HER2 3+, Ki-67 30%). After surgery, the patient was given trastuzumab therapy.

UR - https://www.scopus.com/pages/publications/85067439112

M3 - Review article

C2 - 31164545

AN - SCOPUS:85067439112

SN - 0385-0684

VL - 46

SP - 814

EP - 816

JO - Japanese Journal of Cancer and Chemotherapy

JF - Japanese Journal of Cancer and Chemotherapy

IS - 4

ER -

A case of an elderly individual with breast cancer diagnosed as Paget's disease after mastectomy

Abstract

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