A case of an elderly individual with breast cancer diagnosed as Paget's disease after mastectomy

Hitomi Kubota, Yuna Suzuki, Keita Adachi, Shuhei Suzuki, Yukiko Hara, Shigeru Fujisaki, Makoto Makishima, Reina Saga, Tomohiro Hirano, Kenichi Sakurai

Research output: Contribution to journalReview articlepeer-review

Abstract

We report here a case of a 78-year-old woman, who underwent mastectomy for breast cancer. Mammography showed a mass in the right MO area with an unclear boundary. Ultrasound examination revealed an irregular mass of 40×29×19 mm in the right C region. Dynamic contrast-enhanced MRI showed a 34 mm tumor with contrast effect in the C area of the right breast. We performed a core needle biopsy on the mass, and the histopathological diagnosis was apocrine carcinoma (ER-, PgR-, HER2 3+, and Ki-67 30%) of clinical T2N0M0, stage HA. Right mastectomy and sentinel lymph node biopsy were performed. In the postoperative pathological examination, the main lesion was apocrine carcinoma (ER-, PgR-, HER2 3+, Ki-67 20%) and Paget's disease (ER-, PgR-, HER2 3+, Ki-67 30%). After surgery, the patient was given trastuzumab therapy.

Original languageEnglish
Pages (from-to)814-816
Number of pages3
JournalJapanese Journal of Cancer and Chemotherapy
Volume46
Issue number4
Publication statusPublished - Apr 2019

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