Research output per year
Research output per year
- 45 results
Search results
-
2024
Investigating the effect of prescribing status and patient characteristics on the therapeutic outcomes in patients with diabetes using a leftover drug adjustment protocol
Hirai, T., Hanaoka, S., Terakado, Y., Seki, T. & Watanabe, F., 2024, In: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques. 27, 12886.Research output: Contribution to journal › Article › peer-review
Open Access -
MS785-MS27 Reactive Misfolded/Non-Native Zn-Deficient SOD1 Species Exhibit Cytotoxicity and Adopt Heterozygous Conformations in Motor Neurons
Tokuda, E., Sakashita, Y., Tokoro, N., Date, A., Kosuge, Y. & Miyasaka, T., Jun 2024, In: International Journal of Molecular Sciences. 25, 11, 5603.Research output: Contribution to journal › Article › peer-review
Open Access -
2023
Anti-Inflammatory Effects of Miyako Bidens pilosa in a Mouse Model of Amyotrophic Lateral Sclerosis and Lipopolysaccharide-Stimulated BV-2 Microglia
Tsuruta, K., Shidara, T., Miyagishi, H., Nango, H., Nakatani, Y., Suzuki, N., Amano, T., Suzuki, T. & Kosuge, Y., Sept 2023, In: International Journal of Molecular Sciences. 24, 18, 13698.Research output: Contribution to journal › Article › peer-review
Open Access -
Application of ionic liquids to intranasal formulation targeting the brain
Suzuki, N., 2023, In: Drug Delivery System. 38, 3, p. 239-245 7 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Exploration and characterization of a novel cocrystal hydrate consisting of captopril, an amino acid-derived drug
Haku, R., Takatori, K., Suzuki, N., Ono, M., Titapiwatanakun, V. & Fukami, T., 2023, (Accepted/In press) In: CrystEngComm.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Internuclear distance measurements between 1H and 14N in multi-component rigid solids at fast MAS
Ogaeri, Y., Suzuki, N., Fukami, T. & Nishiyama, Y., Mar 2023, In: Journal of Magnetic Resonance. 348, 107378.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Shared decision-making practices and patient values in pharmacist outpatient care for rheumatic disease: A multiple correspondence analysis
Hirata, I., Hanaoka, S., Rokutanda, R., Funakoshi, R. & Hayashi, H., 2023, In: Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques. 26, p. 11135 1 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Citations (Scopus) -
Utility of a Novel Micro-Spraying Device for Intranasal Administration of Drug Solutions to Mice
Suzuki, N., Tanigawa, H., Nagatomo, T., Miyagishi, H., Kanazawa, T., Suzuki, T. & Kosuge, Y., Nov 2023, In: Pharmaceutics. 15, 11, 2553.Research output: Contribution to journal › Article › peer-review
Open Access -
2022
Application of ionic liquid to enhance the nose-to-brain delivery of etodolac
Tanigawa, H., Suzuki, N. & Suzuki, T., 1 Nov 2022, In: European Journal of Pharmaceutical Sciences. 178, 106290.Research output: Contribution to journal › Article › peer-review
Open Access11 Citations (Scopus) -
Correlation between magnesium pre-loading and cisplatin-induced nephrotoxicity in 5-fluorouracil/cisplatin combination therapy for esophageal cancer
Sugisaki, T., Aoyama, T., Kawakami, K., Yokokawa, T., Kobayashi, K., Suzuki, W., Ogura, M., Ichimura, T., Chin, K., Yamaguchi, K., Hanaoka, S., Hayashi, H. & Yamaguchi, M., Feb 2022, In: Pharmazie. 77, 2, p. 85-88 4 p.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Diversity and Distribution of Aspergillus fumigatus and Its Related Species in Izu and Ogasawara Islands, Japan
Hirose, D., Watanabe, K., Hagiuda, R., Tachikawa, R., Kamijo, T., Yaguchi, T. & Hirota, M., 2022, In: Medical Mycology Journal. 63, 4, p. 99-107 9 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
クロベタゾールプロピオン酸エステル軟膏の製剤特性及びヘパリン類似物質油性クリームとの混合物における基剤安定性に関する検証
Translated title of the contribution :Evaluation of the Pharmaceutical Properties of Clobetasol Propionate Ointments and Base Stability of the Mixture with Heparinoid Oil Based Creams Research output: Contribution to journal › Article › peer-review
Open Access -
2021
A metal-free, disulfide oxidized form of superoxide dismutase 1 as a primary misfolded species with prion-like properties in the extracellular environments surrounding motor neuron-like cells
Takashima, C., Kosuge, Y., Inoue, M., Ono, S. I. & Tokuda, E., 2 Apr 2021, In: International Journal of Molecular Sciences. 22, 8, 4155.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
A novel Mariannaea species isolated from decayed pine needles in Japan
Watanabe, K. & Hirose, D., 11 Oct 2021, In: Phytotaxa. 522, 3, p. 211-220 10 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
Apoptotic Effects of a Thioether Analog of Vitamin K3 in a Human Leukemia Cell Line
Asami, S., Suzuki, M., Nakayama, T., Shimoda, Y., Miura, M., Kato, K., Tokuda, E., Ono, S., Kawakubo, T., Nishizawa, K., Yamanaka, K. & Suzuki, T., Dec 2021, In: International Journal of Toxicology. 40, 6, p. 517-529 13 p.Research output: Contribution to journal › Article › peer-review
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Monitoring of cocrystal dissociation during the wet granulation process in the presence of disintegrants by using low-frequency raman spectroscopy
Suzuki, N., Fukui, K., Otaka, K., Suzuki, T. & Fukami, T., 1 Sept 2021, In: Chemical and Pharmaceutical Bulletin. 69, 9, p. 877-885 9 p.Research output: Contribution to journal › Article › peer-review
Open Access7 Citations (Scopus) -
Quantitative analysis of inulin distribution in the brain focused on nose-to-brain route via olfactory epithelium by reverse esophageal cannulation
Fukuda, M., Kanazawa, T., Iioka, S., Oguma, T., Iwasa, R., Masuoka, S., Suzuki, N., Kosuge, Y. & Suzuki, T., 10 Apr 2021, In: Journal of Controlled Release. 332, p. 493-501 9 p.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
Ubiquitous distribution of azole-resistant aspergillus fumigatus-Related species in outdoor environments in Japan
Watanabe, K., Yaguchi, T. & Hirose, D., 2021, In: Medical Mycology Journal. 62, 4, p. 71-78 8 p.Research output: Contribution to journal › Article › peer-review
Open Access5 Citations (Scopus) -
2020
Crystal Structure Analysis and Pharmaceutical Properties of Amide Salts Consisting of Paracetamol/Sulfonic Acids as Solid Forms Prepared by Grinding
Suzuki, N., Kanazawa, T., Takatori, K., Suzuki, T. & Fukami, T., 5 Feb 2020, In: Crystal Growth and Design. 20, 2, p. 590-599 10 p.Research output: Contribution to journal › Article › peer-review
8 Citations (Scopus) -
Does wild-type Cu/Zn-superoxide dismutase have pathogenic roles in amyotrophic lateral sclerosis?
Furukawa, Y. & Tokuda, E., 19 Aug 2020, In: Translational Neurodegeneration. 9, 1, 33.Research output: Contribution to journal › Review article › peer-review
Open Access23 Citations (Scopus) -
Histamine-2 receptor antagonists (H2RA) may negatively impact ADL assessment in patients on a convalescent rehabilitation ward
Hanaoka, S., Endo, A., Hayashi, H., Hirai, T. & Seki, T., Mar 2020, In: Pharmazie. 75, 2-3, p. 82-89 8 p.Research output: Contribution to journal › Article › peer-review
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Intranasal administration
Suzuki, N., Kanazawa, T. & Suzuki, T., 2020, In: Drug Delivery System. 35, 1, p. 76-80 5 p.Research output: Contribution to journal › Comment/debate
Open Access1 Citation (Scopus) -
Mariannamides A and B, new cyclic octapeptides isolated from Mariannaea elegans NBRC102301
Ishiuchi, K., Hirose, D., Kondo, T., Watanabe, K., Terasaka, K. & Makino, T., 15 Feb 2020, In: Bioorganic and Medicinal Chemistry Letters. 30, 4, 126946.Research output: Contribution to journal › Article › peer-review
6 Citations (Scopus) -
動的接触角及びサーモグラフィックアプローチを組み合わせた水浸透速度の新規評価法の確立:口腔内崩壊錠における崩壊特性の重要性
Translated title of the contribution :Establishment of a novel method to evaluate water permeation rates by combining the dynamic contact angle and thermographic approach: Significance of disintegration properties of orally disintegrating tablets Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
2019
Imaging Analysis Enables Differentiation of the Distribution of Pharmaceutical Ingredients in Tacrolimus Ointments
Fujii, M. Y., Yamamoto, Y., Koide, T., Hamaguchi, M., Onuki, Y., Suzuki, N., Suzuki, T. & Fukami, T., 1 Oct 2019, In: Applied Spectroscopy. 73, 10, p. 1183-1192 10 p.Research output: Contribution to journal › Article › peer-review
5 Citations (Scopus) -
Isochromophilol A, a new azaphilone isolated from Penicillium sp. RO369, a leaf litter inhabiting fungus from Tsuga diversifolia
Ishiuchi, K., Hirose, D., Takahashi, Y., Miyagawa, R., Watanabe, K. & Kitanaka, S., 2019, In: Heterocycles. 98, 11, p. 1574-1579 6 p.Research output: Contribution to journal › Article › peer-review
Open Access1 Citation (Scopus) -
Optimum volume of water needed for the paste state of pediatric powders: Considerations based on yield values and applications to generic medicine
Fukuda, H., Suzuki, T., Hashizaki, K., Yoshimura, S., Kobayashi, C., Omotani, Y., Suzuki, N., Kanazawa, T., Fukami, T. & Yamamoto, Y., 2019, In: Yakugaku Zasshi. 139, 2, p. 299-308 10 p.Research output: Contribution to journal › Article › peer-review
Open Access3 Citations (Scopus) -
2018
Comparison of the relative stability of pharmaceutical cocrystals consisting of paracetamol and dicarboxylic acids
Suzuki, N., Kawahata, M., Yamaguchi, K., Suzuki, T., Tomono, K. & Fukami, T., 3 Apr 2018, In: Drug Development and Industrial Pharmacy. 44, 4, p. 582-589 8 p.Research output: Contribution to journal › Article › peer-review
18 Citations (Scopus) -
Mixtures of betamethasone butyrate propionate ointments and heparinoid oil-based cream: Physical stability evaluation
Yamamoto, Y., Hanai, A., Onuki, Y., Fujii, M., Onishi, Y., Fukami, T., Metori, K., Suzuki, N., Suzuki, T. & Koide, T., 1 Nov 2018, In: European Journal of Pharmaceutical Sciences. 124, p. 199-207 9 p.Research output: Contribution to journal › Article › peer-review
9 Citations (Scopus) -
Molecular state of active pharmaceutical ingredients in ketoprofen dermal patches characterized by pharmaceutical evaluation
Azuma, M., Fujii, M., Inoue, M., Hisada, H., Koide, T., Kemper, M., Yamamoto, Y., Suzuki, N., Suzuki, T. & Fukami, T., 2018, In: Biological and Pharmaceutical Bulletin. 41, 9, p. 1348-1354 7 p.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Novel methods for intranasal administration under inhalation anesthesia to evaluate nose-to-brain drug delivery
Kanazawa, T., Fukuda, M., Suzuki, N. & Suzuki, T., Nov 2018, In: Journal of Visualized Experiments. 2018, 141, e58485.Research output: Contribution to journal › Article › peer-review
15 Citations (Scopus) -
2016
Involvement of a proton-coupled organic cation antiporter in the blood–brain barrier transport of amantadine
Suzuki, T., Aoyama, T., Suzuki, N., Kobayashi, M., Fukami, T., Matsumoto, Y. & Tomono, K., Sept 2016, In: Biopharmaceutics and Drug Disposition. 37, 6, p. 323-335 13 p.Research output: Contribution to journal › Article › peer-review
13 Citations (Scopus) -
2015
Regulation of Intracellular Copper by Induction of Endogenous Metallothioneins Improves the Disease Course in a Mouse Model of Amyotrophic Lateral Sclerosis
Tokuda, E., Watanabe, S., Okawa, E. & Ono, S. I., 1 Apr 2015, In: Neurotherapeutics. 12, 2, p. 461-476 16 p.Research output: Contribution to journal › Article › peer-review
Open Access22 Citations (Scopus) -
2014
A possible novel pharmacological therapy for Parkinson's disease using the pleiotropic property of Selegiline
Ono, S. I., Sorte, R. & Tokuda, E. I., 2014, In: Current Topics in Pharmacology. 18, 1-2, p. 29-37 9 p.Research output: Contribution to journal › Article › peer-review
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Overexpression of metallothionein-I, a copper-regulating protein, attenuates intracellular copper dyshomeostasis and extends lifespan in a mouse model of amyotrophic lateral sclerosis caused by mutant superoxide dismutase-1
Tokuda, E., Okawa, E., Watanabe, S. & Ono, S. I., Mar 2014, In: Human Molecular Genetics. 23, 5, ddt517.Research output: Contribution to journal › Article › peer-review
34 Citations (Scopus) -
2013
Processing and formulation of drug nanoparticles by ternary cogrinding with methacrylic copolymer and sucrose fatty acid esters
Hida, Y., Fukami, T., Suzuki, N., Suzuki, T. & Tomono, K., Jan 2013, In: Advanced Powder Technology. 24, 1, p. 246-251 6 p.Research output: Contribution to journal › Article › peer-review
2 Citations (Scopus) -
2012
An attempt to treat amyotrophic lateral sclerosis by intracellular copper modification using ammonium tetrathiomolybdate and/or metallothionein: Fundamentals and perspective
Ono, S. I., Tokuda, E. I., Okawa, E. & Watanabe, S., 31 Jul 2012, Brain Diseases and Metalloproteins. Pan Stanford Publishing Pte. Ltd., p. 367-405 39 p.Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review
1 Citation (Scopus) -
2009
Dysregulation of intracellular copper trafficking pathway in a mouse model of mutant copper/zinc superoxide dismutase-linked familial amyotrophic lateral sclerosis
Tokuda, E., Okawa, E. & Ono, S. I., Oct 2009, In: Journal of Neurochemistry. 111, 1, p. 181-191 11 p.Research output: Contribution to journal › Article › peer-review
Open Access49 Citations (Scopus) -
Effects of pergolide mesilate on metallothionein mRNAs expression in a mouse model for Parkinson disease
Ono, S. I., Hirai, K. & Tokuda, E. I., Oct 2009, In: Biological and Pharmaceutical Bulletin. 32, 10, p. 1813-1817 5 p.Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (Scopus) -
Nanoparticle processing in the solid state dramatically increases the cell membrane permeation of a cholesterol-lowering drug, probucol
Fukami, T., Ishii, T., Io, T., Suzuki, N., Suzuki, T., Yamamoto, K., Xu, J., Ramamoorthy, A. & Tomono, K., 1 Jun 2009, In: Molecular Pharmaceutics. 6, 3, p. 1029-1035 7 p.Research output: Contribution to journal › Article › peer-review
27 Citations (Scopus) -
2008
Ammonium tetrathiomolybdate delays onset, prolongs survival, and slows progression of disease in a mouse model for amyotrophic lateral sclerosis
Tokuda, E., Ono, S. I., Ishige, K., Watanabe, S., Okawa, E., Ito, Y. & Suzuki, T., Sept 2008, In: Experimental Neurology. 213, 1, p. 122-128 7 p.Research output: Contribution to journal › Article › peer-review
51 Citations (Scopus) -
2007
Different patterns in the induction of metallothionein mRNA synthesis among isoforms after acute ethanol administration
Ono, S. I., Ishizaki, Y., Tokuda, E. I., Tabata, K. I., Asami, S. & Suzuki, T., Feb 2007, In: Biological Trace Element Research. 115, 2, p. 147-156 10 p.Research output: Contribution to journal › Article › peer-review
12 Citations (Scopus) -
Dysequilibrium between caspases and their inhibitors in a mouse model for amyotrophic lateral sclerosis
Tokuda, E., Ono, S. I., Ishige, K., Watanabe, S., Okawa, E., Ito, Y. & Suzuki, T., 7 May 2007, In: Brain Research. 1148, 1, p. 234-242 9 p.Research output: Contribution to journal › Article › peer-review
16 Citations (Scopus) -
Metallothionein proteins expression, copper and zinc concentrations, and lipid peroxidation level in a rodent model for amyotrophic lateral sclerosis
Tokuda, E., Ono, S. I., Ishige, K., Naganuma, A., Ito, Y. & Suzuki, T., 5 Jan 2007, In: Toxicology. 229, 1-2, p. 33-41 9 p.Research output: Contribution to journal › Article › peer-review
72 Citations (Scopus) -
2006
Upregulation of metallothionein-I mRNA expression in a rodent model for amyotrophic lateral sclerosis
Ono, S. I., Endo, Y., Tokuda, E. I., Ishige, K., Tabata, K. I., Asami, S., Ito, Y. & Suzuki, T., Oct 2006, In: Biological Trace Element Research. 113, 1, p. 93-103 11 p.Research output: Contribution to journal › Article › peer-review
16 Citations (Scopus)